The Medical Saints between faith, fair and big concerts in the square
Saints Cosma and Damiano, the famous Medical Saints who, according to tradition, treated the sick for free, are venerated in Isernia as secondary patrons. Their feast day, September 26th, is one of the most heartfelt events in the capital of Molise and the culmination of the so-called Settembre Isernino.
The religious program includes the pontifical mass presided over by the Bishop of Isernia-Venafro and the solemn procession through the streets of the center. Devotion to the Medical Saints unites Isernia with other communities in the area, with faithful also coming from Sant'Elia Fiumerapido, in a bond that strengthens ties between the towns.
On September 26th and 27th, the traditional fair dedicated to crafts, typical products, and various goods comes alive in the streets of the historic center, filling the heart of the city with music and colors. A characteristic of the festival is the big evening concert in the square: an established tradition that over the years has brought Italian music stars to Isernia, transforming the patronal feast into an event of attraction for the entire province.
The Festival of Saints Cosma and Damiano 2026 in Isernia has its religious heart on September 26th, with the pontifical mass presided over by the Bishop and the solemn procession through the historic center. On September 26th and 27th, the streets of the center host the traditional fair dedicated to crafts, typical products, and various goods.
Among the most anticipated events is the evening concert on September 26th in the square with Coontrasto, the official cover band of the Poohs, which brings the patronal feast to its most popular and attractive dimension.
The evening concert on September 26th with Coontrasto (official Poohs cover band); the pontifical mass and procession; the traditional fair.
The celebrations and the fair take place in the historic center of Isernia, which is accessible on foot. Isernia is connected by car via the SS17 and SS650 Trignina and by train on the Rome-Campobasso-Isernia line.
During the procession and concerts, traffic changes are expected in the historic center. Concerts in the square and the fair have free admission.
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Cattedrale di San Pietro Apostolo e centro storico
Centro storico, 86170 Isernia